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姚守拙院士个人简介

姚守拙 Shouzhuo Yao
教授,博士生导师,中国科学院院士
Tel: 86-731-88821968
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研究方向:生命、环境及材料科学中的新分析方法

Research Interest: New analytical methods in biological, environmental, and material sciences

1936年出生,1959年毕业于原苏联列宁格勒大学放射化学研究所。1999年被评为中国科学院化学部院士。国家药典委员会执行委员。《中国科学》编委。长期从事基础理论与应用研究,在发展交叉学科并应用于新型化学与生物传感器、中药现代化等方面开展了一系列创新而富有成效的研究。开拓出压电液相振荡化学传感新领域,是80年代初国际上首先在此领域实现突破,使压电晶体在液相介质中稳定振荡并成功用于化学测定的极少数科技工作者之一。近年来开展了中草药现代化、食品安全和生化分析仪器等领域研究,并取得了多项研究成果。已在国内外重要学术刊物上发表论文400余篇。先后主持并完成多项国家重大科研项目,获国家、省部委科技成果奖9项,曾获机械工业部高校科技突出贡献奖,全国优秀科技工作者,全国教育系统劳动模范等。

Born in 1936, graduated from Institute of Radiochemistry, Leningrad University (now Petersburg University) in 1959. He was elected as the academician of the Chinese Academy of Sciences in 1999. The focus of his research is on developing new chemo/biosensors and other analytical methods in biological, environmental, and material sciences, modernization of Chinese traditional medicine, etc. He has pioneered the use of piezoelectric sensors in liquid environments. He has published more than 400 papers and received a number of national and ministerial awards.

Selected Publications:
1.Liu Q, Wu KK, Tang F, Yao LH, Yang F, Nie Z, Yao SZ*. Amino acid ionic liquids as chiral ligands in ligand-exchange chiral separations. Chem. Eur. J., 2009, 15, 9889-9896.
2.Liu Q, Yao LH, Shen QP, Nie Z, Guo ML, Yao SZ*. Layer-by-layer assembly of polyelectrolyte and nanoparticles, monitored by capillary electrophoresis. Chem. Eur. J., 2009, 15, 12828-12836.
3.Pan YL, Guo ML*, Nie Z, Huang Y, Pan CF, Zeng K, Zhang Y, Yao SZ*. Selective collection and detection of leukemia cells on a magnet-quartz crystal microbalance system using aptamer-conjugated magnetic beads. Biosens. Bioelectron., 2010, 25, 1609–1614.
4.Chen YZ, Wu MH, Wang KY, Chen B, Yao SZ*, Zou HF**, Nie LH. Vinyl  functionalized  silica  hybrid  monolith-based  trypsin  microreactor  for  on line  digestion  and  separation  via  thiol-ene  “click”  strategy. J. Chromatogr. A., 2011, 1218 ,7982– 7988.
5.Chen YZ, Wang KY, Yang HH, Liu YX, Yao SZ*, Chen B, Nie LH, Xu GM. Synthesis of   sulfo/vinyl biphasic silica hybrid monolithic capillary column and its application to on-column preconcentration for capillary electrochromatography. J. Chromatogr. A, 2012, 1233:91-99.
6.Liu YX, Chen YZ, Yang HH, Nie LH, Yao SZ*. Cage-like silica nanoparticles-functionalized silica hybrid monolithfor high performance capillary electrochromatography via “one-pot”process. J. Chromatogr. A, 2013, 1283, 132–139.
7.Huang Y, Wang W, Zou Li, Qin XL, Bu LJ, Tang ZY, Fu YC, Ma, Xie QJ *, Yao SZ*, Hu JM. Horseradish peroxidase-catalyzed synthesis of poly(thiophene-3-boronic acid) biocomposites for mono-/bi-enzyme immobilization and amperometric biosensing. Biosens. Bioelectron., 2013, 44, 41-47.
8.Yan ZH, Cai Y, Zhu GH, Yuan JB, Tu LD, Chen CY, Yao SZ*. Synthesis  of  3-fluorobenzoyl  chloride  functionalized  magnetic sorbent  for  highly  efficient  enrichment  of  perfluorinated  compounds from  river  water  samples. J. Chromatogr. A, 2013, 1321, 21-29.
9.Pan YL, Shan WQ, Fang HT, Guo ML*, Nie Z, Huang Y, Yao SZ*. Sensitive and visible detection of apoptotic cells on Annexin-V modified substrate using aminophenylboronic acid modified gold nanoparticles (APBA-GNPs) labeling. Biosens. Bioelectron., 2014, 52, 62–68.
10.Liu X, Li Y, Xu XH, Li P, Nie Z*, Huang Y, Yao SZ*. Nanomaterial-based tools for protein kinase bioanalysis. Trends Anal. Chem., 2014, 58, 40-53.