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楚霞教授个人简介

 

楚霞 Xia Chu
教授,博士生导师,国家杰出青年基金获得者
Tel: 86-731-88821916
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研究方向: 生物传感与生物分析
Research Interest: Biosensing and Bioanalysis

 

1972年出生。1993年本科毕业于湖南大学化学系,分别于1996年和1999年获得湖南大学化学化工学院硕士和博士学位。1999年至2005年于湖南师范大学化学化工学院工作。2006年调入湖南大学化学生物传感与计量学国家重点实验室工作,任教授,2007年遴选为博士生导师。获教育部新世纪优秀人才支持计划,湖南省杰出青年基金,2015年获得国家自然科学基金委杰出青年科学基金。先后主持国家自然科学基金面上项目4项,研究方向为生物传感与生化分析,在活细胞成像、免疫传感、核酸传感的新方法方面取得了系列创新性的研究成果。以通讯作者身份在JACS、 Angew. Chem. Int. Ed.、 Analytical Chemistry、Chemical Communication等国际重要SCI期刊上发表论文40余篇(影响因子IF>5的论文14篇),引用1558次,单篇最高引用103次。
Born in 1972, professor at Hunan University. Graduated from College of Chemistry and Chemical Engineering of Hunan University in 1993, and received MS in 1996, and PhD in 1999. From 1999 to 2005, work at College of Chemistry and Chemical Engineering of Hunan Normal University. Since 2006, work at State Key Laboratory of Chemo/Biosensing and Chemometrics at Hunan University. Research interests concern the biosensing and bioanalysis of protein and nucleic acid with more than 40 publications.

 

Selected Publications:  
1. Tingting Chen, Yihui Hu, Yao Cen, Xia Chu,* and Yi Lu, A Dual-Emission Fluorescent Nanocomplex of Gold-Cluster-Decorated Silica Particles for Live Cell Imaging of Highly Reactive Oxygen Species. J. Am. Chem. Soc. 2013, 135, 11595−11602.
2. Haibo Wang, Qing Zhang, Xia Chu,* Tingting Chen, Jia Ge, and Ruqin Yu, Graphene Oxide–Peptide Conjugate as an Intracellular Protease Sensor for Caspase-3 Activation Imaging in Live Cells. Angew. Chem. Int. Ed. 2011, 50, 7065 –7069.
3. Li-Juan Ou, Pei-Yan Jin, Xia Chu,* Jian-Hui Jiang, and Ru-Qin Yu, Sensitive and Visual Detection of Sequence-Specific DNA-Binding Protein via a Gold Nanoparticle-Based Colorimetric Biosensor. Anal. Chem. 2010, 82, 6015–6024.
4. Jishan Li, Ting Deng, Xia Chu,* Ronghua Yang,* Jianhui Jiang, Guoli Shen, and Ruqin Yu, Rolling Circle Amplification Combined with Gold Nanoparticle Aggregates for Highly Sensitive Identification of Single-Nucleotide Polymorphisms. Anal. Chem. 2010, 82, 2811–2816.
5. Li-Juan Ou, Si-Jia Liu, Xia Chu,* Guo-Li Shen, and Ru-Qin Yu, DNA Encapsulating Liposome Based Rolling Circle Amplification Immunoassay as a Versatile Platform for Ultrasensitive Detection of Protein. Anal. Chem. 2009, 81, 9664–9673.
6.Long Zhou, Li-Juan Ou, Xia Chu,* Guo-Li Shen, and Ru-Qin Yu, Aptamer-Based Rolling Circle Amplification: A Platform for Electrochemical Detection of Protein. Anal. Chem. 2007, 79, 7492-7500.
7. Hai-bo Wang, Shuang Wu, Xia Chu* and Ru-Qin Yu, A Sensitive Fluorescence Strategy for Telomerase Detection in Cancer Cells Based on T7 Exonuclease-Assisted Target Recycling Amplification. Chem. Commun., 2012, 48, 5916–5918.
8. Zi Yi, Xiao-Yan Li, Feng-Juan Liu, Pei-Yan Jin, Xia Chu*, and Ru-Qin Yu, Design of Label-free, Homogeneous Biosensing Platform Based on Plasmonic Coupling and Surface-Enhanced Raman Scattering Using Unmodified Gold Nanoparticles. Biosensors and Bioelectronics 2013, 43, 308–314.
9. Haibo Wang, Tingting Chen, Shuang Wu, Xia Chu*, and Ruqin Yu, A Novel Biosensing Strategy for Screening G-quadruplex Ligands Based on Graphene Oxide Sheets. Biosensors and Bioelectronics 2012, 34, 88– 93.
10. Danhong Wu, Qing Zhang, Xia Chu,* Haibo Wang, Guoli Shen, Ruqin Yu, Ultrasensitive Electrochemical Sensor for Mercury (II) Based on Target-Induced Structure-Switching DNA. Biosensors and Bioelectronics 2010, 25, 1025–1031.