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羊小海教授个人简介

 

羊小海 Xiaohai Yang
教授,博士生导师 教育部新世纪优秀人才
Tel: +86-731-88823930
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研究方向:纳米及分子水平上的生物分析化学
Research Interest: Bioanalytical chemistry on nanometer and molecule level

1971年生,2000年于湖南大学获分析化学理学博士学位后留校任教。2002-2004年于东京大学从事博士后研究。2007年起任生物纳米与分子工程湖南省重点实验室主任,2017年起任化学生物传感与计量学国家重点实验室副主任。2008获“湖南省杰出青年科学基金”资助,2009年获教育部“新世纪优秀人才支持计划”资助。2003年获湖南省科技进步一等奖(排名第五),2009年获湖南省自然科学一等奖(排名第三),2011年获国家自然科学二等奖(排名第三)。主要从事纳米和分子水平上的生物分析化学、光化学和生物传感器等领域研究。
He was born in 1971, obtained Ph.D. from Hunan University in 2000, and undertook post-doctoral studies at the University of Tokyo in Japan from 2002 to 2004. He has been a professor at Hunan University since 2006. He was the gainer of Outstanding Youth Foundation of Hunan Province (2008) and Program for New Century Excellent Talents in University of Ministry of Education (2009). In 2009 and 2011, he earned the Natural Science Award of Hunan Province (1st Class, 3rd-ranked) and the National Natural Science Award (2nd Class, 3rd-ranked), respectively. His research is mainly focused on bioanalytical chemistry on the nanometer scale and single-molecule level for applications in nanobiotechnology.

Selected Publications:
1.Wenshan Li, Xiaohai Yang*, Leiliang He, Kemin Wang*, Qing Wang, Jin Huang, Jianbo Liu, Bin Wu, and Congcong Xu, "Self-Assembled DNA Nanocentipede as Multivalent Drug Carrier for Targeted Delivery," ACS APPL MATER INTER 8 (39), 25733-25740 (2016).
2.Nandi Chen, Shiya Qin, Xiaohai Yang*, Qing Wang, Jin Huang, and Kemin Wang*, "“Sense-and-Treat” DNA Nanodevice for Synergetic Destruction of Circulating Tumor Cells," ACS APPL MATER INTER 8 (40), 26552-26558 (2016).
3.Bin Wu‡, Rui Jiang‡, Qing Wang, Jin Huang, Xiaohai Yang*, Kemin Wang*, Wenshan Li, Nandi Chen, and Qing Li, "Detection of C-reactive protein using nanoparticle-enhanced surface plasmon resonance using an aptamer-antibody sandwich assay," CHEM COMMUN 52 (17), 3568-3571 (2016).
4.Nandi Chen, Xiaohai Yang*, Qing Wang, Lixin Jian, Hui Shi, Shiya Qin, Kemin Wang*, Jin Huang, and Wenjing Liu, "Proof of concept for inhibiting metastasis: circulating tumor cell-triggered localized release of anticancer agent via a structure-switching aptamer," CHEM COMMUN 52 (41), 6789-6792 (2016).
5.Meng Yang, Xiaohai Yang*, Kemin Wang*, Qing Wang, Xin Fan, Wei Liu, Xizhen Liu, Jianbo Liu, and Jin Huang, "Tuning Transport Selectivity of Ionic Species by Phosphoric Acid Gradient in Positively Charged Nanochannel Membranes," ANAL CHEM 87 (3), 1544-1551 (2015).
6.Leiliang He, Xiaohai Yang*, Fang Zhao, Kemin Wang*, Qing Wang, Jianbo Liu, Jin Huang, Wenshan Li, and Meng Yang, "Self-Assembled Supramolecular Nanoprobes for Ratiometric Fluorescence Measurement of Intracellular pH Values," ANAL CHEM 87 (4), 2459-2465 (2015).
7.Pei Liu, Shan Sun, Xiaochen Guo, Xiaohai Yang*, Jin Huang, Kemin Wang*, Qing Wang, Jianbo Liu, and Leiliang He, "Competitive Host–Guest Interaction between β-Cyclodextrin Polymer and Pyrene-Labeled Probes for Fluorescence Analyses," ANAL CHEM 87 (5), 2665-2671 (2015).
8.Qing Wang, Lin Liu, Xiaohai Yang*, Kemin Wang*, Nandi Chen, Chenchen Zhou, Bianxia Luo, and Shasha Du, “Evaluation of Medicine Effects on the Interaction of Myoglobin and Its Aptamer or Antibody Using Atomic Force Microscopy,” ANAL CHEM 87 (4), 2242-2248 (2015).
9.Min Lin, Wenshan Li, Yaning Wang, Xiaohai Yang*, Kemin Wang*, Qing Wang, Pei Wang, Yujie Chang, and Yuyu Tan, "Discrimination of hemoglobins with subtle differences using an aptamer based sensing array," CHEM COMMUN 51 (39), 8304-8306 (2015).
10.Chunxia Song, Xiaohai Yang*, Kemin Wang*, Qing Wang, Jianbo Liu, Jin Huang, Leiliang He, Pei Liu, Zhihe Qing, and Wei Liu, "A sensitive detection of T4 polynucleotide kinase activity based on [small beta]-cyclodextrin polymer enhanced fluorescence combined with an exonuclease reaction," CHEM COMMUN 51 (10), 1815-1818 (2015).