1. Hai-Feng Yang, Jie Feng, Yan-Li Liu, Yu Yang, Zong-Rang Zhang, Guo-Li Shen, Ru-Qin Yu*，Electrochemical and Surface Enhanced Raman Scattering Spectroelectrochemical Study of Phytic Acid on the Silver Electrode，Journalof Physical Chemistry B 2004, 108, 17412-17417.
2. Qi Shen, Jian-Hui Jiang, Chen-Xu Jiao, Wei-Qi Lin, Guo-Li Shen, Ru-Qin Yu*，Hybridized Particle Swarm Algorithm for Adaptive Structure Training of Multilayer Feed-Forward Neural Network: QSAR Studies of Bioactivity of Organic Compounds，Journal of Computational Chemistry, 2004, 25, 1726-1735.
3. Qi Shen, Jian-Hui Jiang, Chen-Xu Jiao, Shuang-Yan Huan, Guo-li Shen, Ru-Qin Yu*，Optimized Partition of Minimum Spanning Tree for Piecewise Modeling by Particle Swarm Algorithm. QSAR Studies of Antagonism of Angiotensin II Antagonists，Journal of Chemical Information and Computer Science, 2004, 44, 2027-2031.
4. Jian-Xia Lü, Qi Shen, Jian-Hui Jiang, Guo-Li Shen, Ru-Qin Yu*，QSAR analysis of cyclooxygenase inhibitor using particle swarm optimization and multiple linear regression，Journal of Pharmaceutical and Biomedical Analysis, 2004, 35, 679 687.
5. Wei-Jun Wang, Yong-Xi Tan, Jian-Hui Jiang, Jian-Zhong Lu, Guo-Li Shen, Ru-Qin Yu*，Clustering based on kernel density estimation: nearest local maximum searching algorithm，Chemometrics and Intelligent Laboratory Systems, 2004, 72, 1 8.
6. Nasser A.M. Barakat, Jian-Hui Jiang, Yi-Zeng Liang, Ru-Qin Yu*，Piece-wise quasi-linear modeling in QSAR and analytical calibration based on linear substructures detected by genetic algorithm，Chemometrics and Intelligent Laboratory Systems, 2004, 72, 73 82
7. Minghui Yang, Yunhui Yang, Bing Liu, Guoli Shen*, Ruqin Yu，Amperometric glucose biosensor based on chitosan with improved selectivity and stability，Sensors and Actuators B, 2004, 101, 269 276.
8. Shuangyan Huan, Chenxu Jiao, Qi Shen, Jianhui Jiang, Guang ming Zeng, Guo he Huang, Guo-li Shen*, Ru-qin Yu，Determination of heavy metal ions in mixed solution by imprinted SAMs，Electrochimica Acta, 2004, 49, 4273 4280.
9. Minghui Yang, Yunhui Yang, Yu Yang, Guoli Shen*, Ruqin Yu，Bienzymatic amperometric biosensor for choline based on mediator thionine in situ electropolymerized within a carbon paste electrode，Analytical Biochemistry, 2004, 334, 127-134.
10. YanLi Liu, Yun Xing, Hai-Feng Yang, Zhi-Min Liu, Yu Yang, Guo-Li Shen, Ru-Qin Yu*，Ethanol gas sensing properties of nano-crystalline cadmium stannate thick films doped with Pt，Analytica Chimica Acta, 2004, 527, 21-26.
11. YanLi Liu, Hua Wang, Yu Yang, ZhiMin Liu, HaiFeng Yang, GuoLi Shen, RuQin Yu*，Hydrogen sulfide sensing properties of NiFe2O4 nanopowder doped with noble metals，Sensors and Actuators B, 2004, 102, 148-154.
12. Yu Yang, Xin Yang, YanLi Liu, ZhiMin Liu, HaiFeng Yang, GuoLi Shen, RuQin Yu*，Optical sensor for lithocholic acid based on multilayered assemblies from polyelectrolyte and cyclodextrin，Journal of Photochemistry and Photobiology A, 2004, 171, 141-148.
13. Yunhui Yang, Minghui Yang, Hua Wang, Jianhui Jiang, Guoli Shen*, Ruqin Yu，An amperometric horseradish peroxidase inhibition biosensor based on a cysteamine self-assembled monolayer for the determination of sulfides，Sensors and Actuators B, 2004, 102, 162 168.
14. Yunhui Yang, Minhui Yang, Hua Wang, Ling Tang, Guoli Shen*, Ruqin Yu，Inhibition biosensor for determination of nicotine，Analytica Chimica Acta, 2004, 509, 151-157.
15. Yunhui Yang, Haifeng Yang, Minghui Yang, Yanli liu, Guoli Shen*, Ruqin Yu，Amperometric glucose biosensor based on a surface treated nanoporous ZrO2/Chitosan composite film as immobilization matrix，Analytica Chimica Acta, 2004, 525, 213 220.
16. Hua Wang, Hui Zeng, Zhimin Liu, Yunhui Yang, Ting Deng, Guoli Shen*, Ruqin
17. Yu*，Immunophenotyping of Acute Leukemia Using an Integrated Piezoelectric Immunosensor Array，Analytical Chemistry, 2004, 76, 2203-2209
18. Haifeng Yang, Zongrang Zhang, Guoli Shen, Ruqin Yu*, In-situ Raman Spectra of an NAD-modified silver electrode at various potentials, J Raman Spectroscopy, 2004, 35, 190-194
19. Haifeng Yang, Yu Yang, Zhimin Liu, Zongrang Zhang, Guoli Shen, Ruqin Yu*, Self-assembled monolayer of NAD at silver surface: a Raman mapping study, Surface Science, 2004, 511, 1-8.
20. Yu Yang, Xin Yang, Chen-Xu Jiao, Hai-Feng Yang, Zhi-Min Liu, Guo-Li Shen a, Ru-Qin Yu*,.Optical sensor for berberine utilizing its intrinsic fluorescence enhanced by the formation of inclusion complex with butylated-b-cyclodextrin, Analytica Chimica Acta, 2004 513, 385 392
21. Yu Yang, Cun-Xi Lei, Zhi-Min Liu, Yan-Li Liu, Guo-Li Shen, Ru-Qin Yu*, Highly Selective Dopamine Determination by Using Carboxymethylated b-Cyclodextrin Polymer Film Modified Electrode, Analytical Letters, 2004, 37, 2267-2282.
22. Rong Ni, Rong-Biao Tong, Can-Cheng Guo, Guo-Li Shen, Ru-Qin Yu*, An anthracene/porphyrin dimer fluorescence energy transfer sensing system for picric acid, Talanta 2004, 63, 251 257
23. Fu-Chun Gong, Lian-hui Tang , Guo-Li Shen, Ru-Qin Yu*, Fluorometric enzyme immunosensing system based on a renewable immunoreaction platform for the detection of Schistosoma japonicum antibody, Talanta, 2004, 62, 735-740.
24. Cheng-Gang Niu, Guan-Ming Zeng, Li-Xin Chen, Guo-Li Shen, Ru-Qin Yu*, Proton “off-on” behaviour of methylpiperazinyl derivative of naphthalimide: a pH sensor based on fluorescence enhancement, Analyst, 2004, 129, 20-24.
25. Chen-Xu Jiao, Cheng-Gang Niu, Shuang-Yan Huan, Qi Shen, Yu Yang , Guo-Li Shen , Ru-Qin Yu*,.A reversible chemosensor for nitrite based on the fluorescence quenching of a carbazole derivative, Talanta, 2004, 64,. 637 643.
26. Li-Xin Chen , Cheng-Gang Niu ,Guang-Ming Zeng, Ge-Ming Zeng,
Guo-Li Shen, Ru-Qin Yu*, Aminobenzothiazole Schiff Base as a Fluorescence Carrier for Sensor Preparation and Furazolidone Assay, Analytical Letters 2004, 36(12), 2609-2622
27. Hua Wang, Cunxi Lei, Jishan Li, Zhaoyang Wu, Guoli Shen, Ruqin Yu. A piezoelectric immunoagglutination assay for Toxoplasma gondii antibodies using gold nanoparticles. Biosensors and. Bioelectronics, 2004, 19(7), 701 709.
28. Jishan Li, Hua Wang, Ting Deng, Zhaoyang Wu, Guoli Shen*., Ruqin Yu , A plasma-polymerized film for capacitance immunosensing, Biosensors and Bioelectronics, 2004, 20, 841 847
29. Hua Wang, Yanli Liu, Yunhui Yang, Ting Deng, Guoli Shen*, Ruqin Yu. A protein A-based orientation- controlled immobilization strategy for antibodies using nanometer-sized gold particles and plasma-polymerized film, Analytical Biochemistry, 2004, 324(2), 219 226.
30. Hua Wang, Jishan Li, Yanjun Ding, Cunxi Lei, Guoli Shen*, Ruqin Yu, Novel immunoassay for Toxoplasma gondii-specific immunoglobulin G using a silica nanoparticle-based biomolecular immobilization method. Analytica Chimica. Acta, 2004, 501(1), 37 43.
31. Hua Wang, Dan Li, Zhaoyang Wu, Guoli Shen*, Ruqin Yu, A reusable piezo-immunosensor with amplified sensitivity for ceruloplasmin based on plasma-polymerized film. Talanta, 2004, 62(1), 201 208.
32. Ting Deng, Hua Wang, Ji-Shan Li, Shun-Qin Hu, Guo-Li Shen*, Ru-Qin Yu,
A novel immunosensor based on self-assembled chitosan/alginate multilayers for the detection of factor B, Sensors and Actuators B, 2004, 99, 123-129.
33. Shuangyan Huana, Hui Chua, Chenxu Jiao, Guangming Zeng,Guohe Huang, Guoli Shen*,.Ruqin Yu, Selective electrochemical molecular recognition of benzenediol isomers using molecularly imprinted TiO2 film electrodes, Analytica Chimica. Acta, 2004, 506, 31 39
34. Shuangyan Huan, Guoli Shen*, Ruqin Yu. Enantioselective recognition of amino acid by differential-pulse voltammetry in molecularly imprinted monolayers assembled on Au electrodes, Electroanalysis, 2004, 16, 1019-1023.
35. Cun-Xi Lei, Yu Yang, Hua Wang , Guo-Li Shen, Ru-Qin Yu*, Amperometric immunosensor for probing complement III (C3) based on immobilizing C3 antibody to a nano-Au monolayer supported by sol gel-derived carbon ceramic electrode, Analytica Chimica Acta，2004, 513, 379-384.
36. Cun-Xi Lei,, Hua Wang, Guo-Li Shen, Ru-Qin Yu*, Immobilization of Enzymes on the Nano-Au Film Modified Glassy Carbon Electrode for the Determination of Hydrogen Peroxide and Glucose, Electroanalysis, 2004, 16, 736-740.
37. Cun-Xi Lei, Jing Wu , Hua Wang , Guo-Li Shen , Ru-Qin Yu*, A new electrochemical immunoassay strategy for detection of transferring based on electrostatic interaction of natural polymers, Talanta, 2004, 63, 469-474.
38. Cun-Xi Lei, Shun-Qin Hu, Na Gao, Guo-Li Shen, Ru-Qin Yu*, An amperometric hydrogen peroxide biosensor based on immobilizing horseradish peroxidase to a nano-Au monolayer supported by sol gel derived carbon ceramic electrode, Bioelectrochemistry, 2004, 65, 33-39.
39. Ji-Lai Gong, Fu-Chun Gong,Ying Kuang, Ge-Ming Zeng, Guo-Li Shen, Ru-Qin Yu*, Capacitive chemical sensor for fenvalerate assay based on electropolymerized molecularly imprinted polymer as the sensitive layer, Analytical and Bioanalytical Chemistry, 2004, 379, 302-307.
40. Zhimin Liu, Hua Wang, Yu Yang, Hai-Feng Yang, Shun-Qin Hu, Na Gao, Guo-Li Shen, Ru-Qin Yu*, Amperometric tyrosinase biosensor using enzyme-labelled nano-Au colloids immobilized on cystamine/chitosan modified gold electrode, Analytical Letters, 2004, 37, 1079-1091.
41. Jian-Hui Jiang, Yizeng Liang, Yukihiro Ozaki*, Principles and methodologies in self-modeling curve resolution, Chemometrics and Intelligent Laboratory Systems, 2004, 71, 1-12.
42. Jian-Hui Jiang, Yukihiro Ozaki*, Michael Kleimann, Heinz W. Siesler, Resolution of two-way data from on-line Fourier-transform Raman spectroscopic monitoring of the anionic dispersion polymerization of styrene and 1,3-butadiene by parallel vector analysis (PVA) and window factor analysis (WFA), Chemometrics and Intelligent Laboratory Systems, 2004, 70, 83-92.
43. QingZhang. Lu, HaiLong. Wu, RuQin. Yu*, GuoLi. Shen, The Lifitime of CFC Substitutes Studied by a Network Trained With Chaotic Mapping Modified Genetic Algorithm and DFT Calculations, SAR and QSAR in Environmental Research, 2004, 15, 279-292.
44. Qi Shen, Jian-Hui Jiang, Chen-Xu Jiao, Guo-Li Shen, Ru-Qin Yu*, .Modified particle swarm optimization algorithm for variable selection in MLR and PLS modeling: QSAR studies of antagonism of angiotensin II antagonists, European Journal of Pharmaceutical Science, 2004, 22, 145-152.
45. Xu-biao Luo, Bo Chen, Shou-zhuo Yao*. High-performance liquid chromatography with electrospray mass spectrometry for rapid and sensitive determination of sanguinarine and chelerythrine in exogenous contaminated honey. Chromatographia, 2004, 60(5-6): 347-351.
46. Ming Ma, Bo Chen, Xubiao Luo, Hao Tan, Dingsheng He, Qingji Xie, Shouzhuo Yao*. Study on the transport selectivity and kinetics of amino acids through di(2-ethylhexyl) phosphoric acid-kerosene bulk liquid membrane. Journal of Membrane Science, 2004, 234: 101-109.
47. Ming Ma, Ai-Hua Shen, Xu-Biao Luo, Xiao-Lan Zhu, Bo Chen, and Shouzhuo Yao*. Solvent Extraction and Liquid-Membrane Transport for Separation and Purification of Rutaecarpine from E. rutaecarpa var. officinalis. Solvent Extraction and Ion Exchange, 2004, 22: 511-525.
48. Hui Li, Bo Chen, Zhaohui Zhang, Shouzhuo Yao*. Focused microwave-assisted solvent extraction and HPLC determination of effective constituents in Eucommia ulmodies Oliv. (E. ulmodies). Talanta 2004， 63 (3): 659-665.
49. Hui Li, Bo Chen, Shouzhuo Yao*. Application of ultrasonic technique for extracting chlorogenic acid from Eucommia ulmodies Oliv. (E. ulmodies). Ultrasonics sonochemistry, 2005, 12: 295-300.
