叶 茂Mao Ye

教授，教育部新世纪优秀人才

Tel: 86-731-88821834

yemaocsu@hotmail.com

研究方向：肿瘤生物学、分子靶向抗肿瘤治疗

Reserch Interest: Tumor biology, Molecular target-guided tumor therapy

中文简介

1972年生。2005年毕业于中南大学湘雅医学院肿瘤研究所，获得医学博士学位。2007年赴美在New York Blood Center从事肿瘤分子病理机制博士后研究。主持国家自然科学基金、浙江省自然科学基金、湖南省自然科学基金、长沙市科技计划等多项，作为co-PI主持美国Rose M.Badgeley Residuary Charitable基金1项。获得教育部2009年度高等学校科学研究优秀成果（自然科学奖）二等奖、湖南省自然科学一等奖、温州市第十三届自然科学优秀论文一等奖。已在Theranostics、Oncotarget、Cancer Letters、FEBS Letters、Invest Ophthalmol Vis Sci等杂志发表科研论文几十篇。2006年入选温州市“新世纪551人才工程”。2007年入选浙江省高校中青年学科带头人。2013年入选教育部新世纪优秀人才。

 Mao Ye， born in 1972，is a full-time professsor in the State Key Laboratory of Chemo/Biosensing and Chemometrics and College of Biology at Hunan University. He obtained Ph.D. from Central South University in 2005, and undertook post-doctoral studies at New York Blood  Center from 2007 to 2010. His research is mainly focused on tumor biology and molecular target-guided tumor therapy.

Selected Publications:  

1. 1. Mridul Roy, Long Liang, Xiaojuan Xiao, Yuanliang Peng, Yuhao Luo, Weihua Zhou, Ji Zhang, Lugui Qiu, Shuaishuai Zhang, Feng Liu, Mao Ye*, Wen Zhou*, Jing Liu*. Lycorine Inhibits Autophagy and Enhances Bortezomib Activity by Inducing Proteasomal Degradation of HMGB1 in Multiple Myeloma. Theranostics .2016; 6(12):2209-2224

2. Wang, Zi; Zhang, Jingxin; Zeng, Yayue; Sun, Shuming; Zhang, Ji; Zhang, Bin; Zhu, Min; Ouyang, Ruoyun; Ma, Bianyin; Ye, Mao*; An, Xiuli*; Liu, Jing*, Knockout of 4.1B triggers malignant transformation in SV40T-immortalized mouse embryo fibroblast cells., Molecular Carcinogenesis, 2016/6/17.

3. Duan, Minlan; Long, Yuqian; Yang, Cai; Wu, Xiaoqiu; Sun, Yang; Li, Jianglin; Hu, Xiaoxiao; Lin, Wei; Han, Dongmei; Zhao, Yifan; Liu, Jing; Ye, Mao*; Tan, Weihong*, Selection and characterization of DNA aptamer for metastatic prostate cancer recognition and tissue imaging., Oncotarget, 2016/5/10.

4. Sun, Yang; Yang, Chao; Chen, Jieying; Song, Xin; Li, Zhen; Duan, Minlan; Li, Jianglin; Hu, Xiaoxiao; Wu, Kuangpei; Yan, Guobei; Yang, Cai; Liu, Jing; Tan, Weihong*;  Ye, Mao*, Overexpression of WDR79 in non-small cell lung cancer is linked to tumour progression., Journal of Cellular and Molecular Medicine, 20(3), 2016/2/5.

5. Long, Yuqian; Qin, Zhiqiang; Duan, Minlan; Li, Shizhu; Wu, Xiaoqiu; Lin, Wei; Li, Jianglin; Zhao, Zilong; Liu, Jing; Xiong, Dehui; Huang, Yi; Hu, Xiaoxiao; Yang, Chao; Ye, Mao*; Tan, Weihong*, Screening and identification of DNA aptamers toward Schistosoma japonicum eggs via SELEX., Scientific Reports, Vol 6, p24986, 2016.

6. Ye, Mao*; Tang, Yani; Tang, Shijun; Liu, Jing; Wu, Kuangpei; Yao, Shan; Sun, Yang; Zhou, Lei; Deng, Tanggang; Chen, Ying; Huang, Chenghan; Tan, Weihong*, STIP is a critical nuclear scaffolding protein linking USP7 to p53-Mdm2 pathway regulation., Oncotarget, 6(33), pp 34718-34731, 2015/10/27.

7. Tang, Yani; Yan, Guobei; Song, Xin; Wu, Kuangpei; Li, Zhen; Yang, Chao; Deng, Tanggang; Sun, Yang; Hu, Xiaoxiao; Yang, Cai; Bai, Huarong; Li, Hui; Tan, Weihong*; Ye, Mao*; Liu, Jing*, STIP overexpression confers oncogenic potential to human non-small cell lung cancer cells by regulating cell cycle and apoptosis., Journal of Cellular and Molecular Medicine, 19(12), pp 2806-2817, 2015/9/10.

8. Wu, Xiaoqiu; Zhao, Zilong; Bai, Huarong; Fu, Ting; Yang, Chao; Hu, Xiaoxiao; Liu, Qiaoling; Champanhac, Carole; Teng, I-Ting; Ye, Mao*; Tan, Weihong*, DNA Aptamer Selected against Pancreatic Ductal Adenocarcinoma for in vivo Imaging and Clinical Tissue Recognition., Theranostics, 5(9), pp 985-994, 2015.

9. Wang, Zi; Ma, Bianyin; Li, Hui; Xiao, Xiaojuan; Zhou, Weihua; Liu, Feng; Zhang, Bin; Zhu, Min; Yang, Qin; Zeng, Yayue; Sun, Yang; Sun, Shuming; Wang, Yanpeng; Zhang, Yibin; Weng, Haibo; Chen, Lixiang; Ye, Mao*; An, Xiuli*; Liu, Jing*, Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC., Oncotarget, 6(33), 2015/11/13.

10. Ye, Mao*; Hu, Jun; Peng, Minyuan; Liu, Jing; Liu, Jun; Liu, Huixia; Zhao, Xielan; Tan, Weihong*, Generating Aptamers by Cell-SELEX for Applications in Molecular Medicine, International Journal of Molecular Sciences, 13(3), pp 3341-3353, 2012/3.